Ion transport and regulation in a synaptic vesicle glutamate transporter

20/05/22 10:37

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Source https://science.sciencemag.org/
URL https://science.sciencemag.org/conten...
シェア日付 2020年05月22日(金) 10時37分16秒 +0900
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Ion
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カテゴリー 学術

コンテンツ概要

Transport dependent on context Transporter proteins move substrates across a membrane, often coupling this activity to cellular ion concentration gradients. For neurotransmitter transporters, which reside in synaptic vesicles that fuse with the plasma membrane after an action potential, transport activity needs to be regulated so that they do not pump out neurotransmitters after vesicle fusion. Using cryo–electron microscopy, Li et al. determined the structure of a vesicular glutamate transp...